p53-Mediated Germ Cell Quality Control in Spermatogenesis
نویسندگان
چکیده
منابع مشابه
p53-dependent programmed necrosis controls germ cell homeostasis during spermatogenesis
The importance of regulated necrosis in pathologies such as cerebral stroke and myocardial infarction is now fully recognized. However, the physiological relevance of regulated necrosis remains unclear. Here, we report a conserved role for p53 in regulating necrosis in Drosophila and mammalian spermatogenesis. We found that Drosophila p53 is required for the programmed necrosis that occurs spon...
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ژورنال
عنوان ژورنال: Developmental Biology
سال: 1998
ISSN: 0012-1606
DOI: 10.1006/dbio.1998.9074